From Utrecht Central Station:

On foot
Hostel Strowis is a 15 minutes walk from Central Station.
Coming from the trains, go upstairs to the station hall. Follow the signs 'Hoog Catharijne/Centrum' and later on 'Binnenstad/ Vredenburg'. At the end of the shopping centre take exit 'Clarenburg' (straight ahead, down the escalator). Cross the square to the left, and turn right into the Lange Viestraat. Cross the bridge over the 'Oude Gracht'. At the 'Neude' -square turn left into the Voorstraat. The Boothstraat is the third street on your right.

By bus
From the trains, follow the signs 'Stadsbussen' (city buses).
City buses will take you every 5 minutes.
Take line 2, 4, 8 or 11 and get out at busstop Janskerkhof.